Book Review


The Sinatra Solution

New Hope for Preventing and Treating Heart Disease

by Stephen Sinatra, M.D., F.A.C.C., F.A.C.N.

Review written by,  Marcus Plourde, Ph.D.


Author Website:


About the Author

Dr. Sinatra is a board-certified cardiologist, certified psychotherapist, and certified in anti-aging medicine.  He has more than 25 years of experience helping patients to prevent and reverse heart disease.

He is a Fellow of the American College of Cardiology and the former Chief of Cardiology at Manchester Memorial Hospital.  Dr. Sinatra has been Director of Medical education at the hospital during the last ten years and also an Assistant Clinical Professor of Medicine at the University of Connecticut School of Medicine.

Dr. Sinatra formulates his own vitamins.  As such, his knowledge about dosages, absorption rates, how to select  quality ingredients, and the effects of combining supplements with cardiac medications, making him uniquely qualified to give advice on nutritional supplements and the heart.  He practices at The New England Heart & Longevity Center in Manchester, CT (860) 643-5101.



If you have not read Heart Sense for Women by Dr. Sinatra, et al., I would suggest reading it first.  It provides a broad foundation of knowledge for women to consider diet, exercise, nutritional supplementation, lifestyle changes, and explains what to avoid in order to maintain a healthy body for 45 and beyond.  The Sinatra Solution reflects the changes in his supplementation recommendations since publishing Heart Sense for Women in 2000.

The Sinatra Solution is a book that will save the lives of many people with heart conditions and circulatory problems.  For many people who are already doing well with their current treatment plan, they may be able improve the quality of their lives and reduce the medications they are taking.  Dr. Sinatra is a Metabolic Cardiologist who believes in using nutritional supplements to complement the traditional medical care of his patients.  He believes that health care providers who integrate the disciplines of biochemical, nutritional, and metabolic solutions will be the healers of the future.  By using this approach in his practice, his patients improve and gain their lives back, rather than being consumed by the progression of their diseases.

After watching his patients return to the emergency room within a few years with the same problems that they had been cured for, he knew there must be more to the process of helping his patients.  His 25 years of exploration and experience has lead him to augment his treatments with four nutritional supplements found in health food stores (co enzyme Q10 or CoQ10, L-carnitine, D-ribose, and magnesium).  He says he rarely sees his patients return for the same problems and is almost never awakened in the middle of the night with patients who need help.  Adding these supplements has made it so that critically ill patients who were waiting for heart transplants and by-pass operations have been healed without needing surgery.  For some, it has allowed reductions in their medications, which reduces some of the uncomfortable side effects from their drugs.  For others, it has improved the quality of lives.

The general concepts associated with heart diseases are that portions of the heart may be depleted of energy and cause a dysfunction.  When the energy of the cells become depleted, dysfunction occurs as portions of the heart go into hibernation in an attempt to rest and restore its energy levels.  As a result, some of the chemical reactions in the process to restore energy to the heart muscle do not take place in the cellular energy pool because some of the necessary nutrients are unavailable or missing. Dr. Sinatra recommends a nutritional supplement cocktail that helps the cells to rebuild and retain the energy they need to operate effectively.

The book details what physically occurs when heart disease is present.  It breaks down how the heart treatment drugs make changes and how the nutrients he adds impact the healing process.

A chapter is dedicated for each nutrient to describe its makeup, what it does, and where it is the most beneficial.  Studies are referenced and detailed to validate their use and efficacy.  This is great information to have and understand if you have one of the health conditions he outlines.

Chapter 8 summarizes the details of The Sinatra Solution and offers suggested doses for the following conditions:

ü        Age-Management (for general preventive maintenance)

ü        High Blood Pressure

ü        Stable Angina Pectoris

ü        Cardiac Arrhythmia—Prevention of Premature Contractions, Premature Atrial Contractions, and Intermittent Atrial Fibrillation

ü        Congestive Heart Failure

ü        Severe Congestive Heart Failure, Dilated Cardiomyopathy, Patients Awaiting Heart Transplantation

ü        Mitral Valve Prolapse

ü        Fibromyalgia, Chronic Fatigue Syndrome, or Mitochondrial Cytopathies

ü        Syndrome X, Insulin Resistance, and Type 2 Diabetes

ü        A Program for Professional or World-class Athletes (muscle pain reduction)

The only potential caution for drug interaction mentioned is with coumadin (blood thinning drugs), as CoQ10 also thins the blood.  In addition, he mentions that statin drugs (cholesterol lowering drugs) deplete the body of co enzyme Q10, which is what causes the muscle fatigue.

Since heart disease is women’s number one killer claiming 1 in 3 women, it would behoove women to read this book and consider following the “Age-Management” protocol for general preventive maintenance.  If a specific condition or disease develops, or is currently present, consider his suggestions.  As always, do this with your attending physician’s knowledge and permission (you may want to purchase a copy of the book for your physician to consider).

This book is a little technical, however it could be a lifesaver.  Today we all need to become our own health care advocates.  Each piece of the complex puzzle that we can gather and utilize with our health care provider to apply to our situation is helpful.  Dr. Sinatra believes, “A good physician assists patients in finding and stimulating there own healing capabilities.” “I’ve learned that real healing takes place when the intention of the healer matches the intention of the patient.”  He also believes, “Nature cures, the doctor only nurses.”  We would all be healthier if more health care providers adopted these types of philosophies.  Hats off to Dr. Sinatra for looking beyond the limitations of just prescribing powerful pharmaceutical drugs, sending patients home, and hoping for the best.

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